منابع مشابه
Inflammation and skeletal metastasis.
On the road to metastasis a cancer cell has to overcome two major obstacles: the physical escape from the primary tumor to a distant tissue and the adaptation to the new microenvironment via colonization and the formation of a secondary tumor. Accumulated scientific findings support the hypothesis that inflammation is a critical component of the tumor microenvironment and develops as a result o...
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The lymphatic vascular system is necessary for the return of extravasated interstitial fluid and macromolecules to the blood circulation, for immune defense, and for the uptake of dietary fats. Impaired functioning of lymphatic vessels results in lymphedema, whereas tumor-associated lymphangiogenesis may contribute to the spread of cancer cells from solid tumors. Recent studies have identified ...
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Objective(s): Neutrophils play an important role in ischemia/reperfusion (IR) induced skeletal muscle injury. Microtubules are required for neutrophil activation in response to various stimuli. This study aimed to investigate the effects of colchicine, a microtubule-disrupting agent, on skeletal muscle IR injury in a rat hindlimb ischemia model. Materials and Methods: Twenty-one Sprague-Dawley ...
متن کاملThe effect of phytochemical compounds on indicators of oxidative stress, inflammation and skeletal muscle damage caused by physical activity
Physical activities are associated with increased production of reactive oxygen species. The production of reactive oxygen species is dependent of the intensity, duration and type of activity. Although the physiological amounts of reactive oxygen species are necessary to regulate cell reactions, their excessive production can cause numerous damages to the structure and function of cells and wea...
متن کاملConventional Radiation Therapy for Skeletal Metastasis
No signifi cant relationship exists between the authors and the companies/organizations whose products or services may be referenced in this article. Introduction Skeletal metastases are common in many types of cancer, and their incidence varies with the primary site. The majority of patients with skeletal metastases experience pain; nevertheless, modern sophisticated imaging and improved asses...
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ژورنال
عنوان ژورنال: BoneKEy Reports
سال: 2015
ISSN: 2047-6396
DOI: 10.1038/bonekey.2015.75